Scientific Director, Department of Ophthalmology
Professor of Ophthalmology and Neurobiology

Education

Rockefeller University, PhD, Neurophysiology and Biophysics 

Duke University, Master of Public Policy

Phone

919-684-8579

Fax

919-684-8829

Email

wong0003@mc.duke.edu

Website

www.duke.edu/~wong0003

Research Interests

The research projects of Fulton Wong, PhD, are aimed at discerning the cellular and molecular signaling mechanisms that operate in and underline a variety of hereditary degenerative disorders of the retina, particularly those types know collectively as retinitis pigmentosa (RP), and using the resulting knowledge to design mechanism-based therapies that are effective and easily available to large groups of patients.

Representative Publications

1. Chang G-Q, Hao Y, Wong F. Apoptosis: Final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron 1993:11:595-605.
2. Huang PC, Gaitan AE, Hao Y, Petters RM, Wong F. Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene. Proc Natl Acad Sci USA 1993:90:8484-8488.
3. Petters RM, Alexander CA, Wells KD, Collins EB, Sommer JR, Blanton MR, Rojas G, Hao Y, Flowers WL, Bannin E, Cideciyan AV, Jacobson SG, Wong F. Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa. Nature Biotech 1997:15:965-970.
4. Peng YW, Hao Y, Petters RM, Wong F. Ectopic synaptogenesis in the mammalian retina caused by rod photoreceptor-specific mutations. Nature Neurosci 2000:3:1121-1127. 
5. Peng YW, Senda T, Hao Y, Matsuno K, Wong F. Ectopic synaptogenesis during retinal degeneration in the RCS rat. Neurosci 2003:119:813-820.