Assistant Professor of Ophthalmology

Education

University of Maryland – College Park, PhD

National Eye Institute, Postdoctoral Training

Phone

919.668.3886

Fax

919.684.9016

Email

hyuncheol.kim@duke.edu

Research Interests

Hyuncheol Kim’s, PhD, research interests are ocular drug delivery. In collaboration with Karl G. Csaky, MD, PhD and Scott W Cousins, MD, Dr. Kim is interested in developing a unique drug delivery system to the retina to increase therapeutic efficacy. In addition, Dr. Kim has focused on understanding the movement of intravitreally or subconjunctivally administered therapeutic agents in the eye.

Dr. Kim is also interested in developing nanotechnology based ocular drug delivery systems in collaboration with Kam Leong, PhD in the biomedical engineering.

Representative Publications

1. Kim H, Robinson MR, Lizak MJ, Tansey G, Lutz RJ, Yuan P, Wang NS, Csaky KG, Controlled drug release from an ocular implant: an evaluation using dynamic three-dimensional magnetic resonance imaging, Invest Ophthalmol Vis Sci. 2004 Aug; 45(8):2722-2731

2. Kim H, Csaky KG, Gilger BC, Dunn JP, Lee SS, Tremblay M, de Monasterio F, Tansey G, Yuan P, Bungay PM, Lutz RJ, Robinson MR, Preclinical evaluation of a novel episcleral cyclosporine implant for ocular graft-versus-host disease, Invest Ophthalmol Vis Sci. 2005 Feb; 46(2):655-662

3. Kim H, Lizak MJ, Tansey G, Csaky KG, Robinson MR, Yuan P, Wang NS, Lutz RJ, Study of ocular transport of drugs released from an intravitreal implant using magnetic resonance imaging, Ann Biomed Eng. 2005 Feb;33(2):150-164

4. Amaral J, Fariss RN, Campos MM, Robinson WG Jr, Kim H, Lutz R, Becerra SP, Transscleral-RPE permeability of PEDF and ovalbumin proteins: implications for subconjunctival protein delivery, Invest Ophthalmol Vis Sci. 2005 Dec; 46(12):4383-4392

5. Robinson MR, Lee SS, Kim H, Kim S, Lutz RJ, Galban C, Bungay PM, Yuan P, Wang NS, Kim J, Csaky KG, A rabbit model for assessing the ocular barriers to the transscleral delivery of triamcinolone acetonide, Exp Eye Res. 2006 Mar;82(3):479-487

6. Kim H, Csaky KG, Chan CC, Bungay PM, Lutz RJ, Dedrick RL, Yuan P, Rosenberg J, Grillo-Lopez AJ, Wilson WH, Robinson MR, The pharmacokinetics of rituximab following an intravitreal injection, Exp Eye Res. 2006 May;82(5):760-766

7. Gilger BC, Salmon JH, Wilkie DA, Cruysberg LP, Kim J, Hayat M, Kim H, Kim S, Yuan P, Lee SS, Harrington SM, Murray PR, Edelhauser HF, Csaky KG, Robinson MR, A novel bioerodible deep scleral lamellar cyclosporine implant for uveitis, Invest Ophthalmol Vis Sci. 2006 Jun; 47(6):2596-2605

8. Kim H, Csaky KG, Gravlin L, Yuan P, Lutz RJ, Bungay PM, Tansey G, DE Monasterio F, Potti GK, Grimes G, Robinson MR, Safety and Pharmacokinetics of a preservative-free triamcinolone acetonide formulation for intravitreal administration, Retina. 2006 May-Jun;26(5):523-530

9. Lee SS, Kim H, Wang NS, Bungay PM, Gilger BC, Yuan P, Csaky KG, Robinson MR, The Pharmacokinetics and Toxicity of a Novel Episcleral Cyclosporine Implant for High Risk Keratoplasties, Invest. Ophth. Vis. Sci. 2007 May;48(5):2023-2029.

10. Kim H, Fariss RN, Zhang C, Robinson SB, Thill M, Csaky KG, Mapping of the Neonatal Fc Receptor in the Rodent Eye, (Accepted to IOVS)