Professor of Ophthalmology Vitreoretinal Diseases and Surgery

Professor of Biomedical Engineering

Medical school

Medical College of Pennsylvania

Residency

Geisinger Medical Center

Fellowship

University of California Davis

Background

Cynthia Toth, MD, specializes in the evaluation and treatment of vitreoretinal diseases. She has pioneered the development of macular translocation surgery for age-related macular degeneration (AMD). Her particular clinical interests and skills also include the surgical treatment of macular diseases, retinal detachment, proliferative diabetic retinopathy, proliferative vitreoretinopathy (PVR), and retinopathy of prematurity (ROP). Toth is involved in national studies of treatment for subretinal neovascularization. Her primary research interests include the development and application of micro-surgical instrumentation and diagnostic tools for vitreoretinal diseases. She has been repeatedly honored among the Best Doctors in America.

Phone

919.684.5631

Fax

919.681.6474

Clinical Interests

• Age-Related Macular Degeneration (AMD)
• Macular Translocation Surgery with 360 degree peripheral retinectomy for treatment of macular diseases such as AMD
• Retinopathy of Prematurity (ROP)
• OCT imaging of retinal pathologies

Research Interests

• Spectral domain and high resolution optical coherence tomography
• Surgical and medical treatments for macular degeneration
• Understanding the early stages of macular degeneration and preventive therapies
• Ophthalmic surgical instrument design and implementation

Representative Publications

1. Toth CA, Morse LS, Hjelmeland LM, Landers MB. Fibrin directs early retinal damage, following experimental subretinal hemorrhage. Arch Ophth 1991, 109:723-729.
2. Toth CA, Birngruber R, Boppart SA, Hee MR, Fujimoto JG, DiCarlo CD, Swanson EA, Cain CP, Narayan DG, Noojin GD, Roach WP. Argon laser retinal lesions evaluated in vivo by optical coherence tomography. Amer J Ophth 1997, 123:188-198.
3. Toth CA, Narayan DG, Boppart SA, Hee MR, Fujimoto JG, Birngruber R, Cain CP, DiCarlo CD, Roach WP. A comparison of retinal morphology viewed by optical coherence tomography and by light microscopy. Arch Ophthalmol. 1997, 115:1425-1428.
4. Toth CA, Freedman SF. Macular translocation with 360-degree peripheral retinectomy: impact of technique and surgical experience on visual outcomes. Retina 2001, 21:293-303.
5. Ting TD, Oh M, Cox TA, Meyer CH, Toth CA. Decreased visual acuity associated with cystoid macular edema in neovascular age-related macular degeneration. Arch Ophthalmol. 2002, 120:731-7. 
6. Park CH, Toth CA. Macular translocation surgery with 360-degree peripheral retinectomy following ocular photodynamic therapy of choroidal neovascularization. Am J Ophthalmol. 2003, 136:830-5.
7. Mruthyunjaya P, Stinnett S, Toth CA. Changes in visual function following macular translocation with 360-degree retinectomy for neovascular age-related macular degeneration. Ophthalmol. 2004 Sep;111(9):1715-24.
8. Cahill MT, Stinnett SS, Banks AD, Freedman SF, Toth CA. Quality of life after macular translocation with 360 degrees peripheral retinectomy for age-related macular degeneration. Ophthalmol. 2005 Jan;112(1):144-51. 
9. Cahill MT, Mruthyunjaya P, Rickman CB, Toth CA. Recurrence of Retinal Pigment Epithelial Changes After Macular Translocation 360 for Geographic Atrophy. Arch Ophthalmol. 2005 Jul;123(7):935-8.
10. Malek G, Johnson LV, Mace BE, Saloupis P, Schmechel DE, Rickman DW, Toth CA, Sullivan PM, Rickman CB. Apolipoprotein E allele-dependent pathogenesis: A model for age-related retinal degeneration. Proc Natl Acad Sci. 2005 Aug;102(33): 11900-5.