|
Professor of Ophthalmology
Vitreoretinal Diseases and Surgery
Medical school
University of California San Francisco
Residency
University of California San Francisco
Fellowship
Medical College of Wisconsin
Background
Glenn Jaffe, MD, specializes in both medical and surgical diseases of
the posterior segment. He also directs the Uveitis Service at the Eye
Center. His surgical interests include proliferate diabetic retinopathy,
retinal detachment, retinal detachment with proliferate
vitreoretinopathy, posterior segment surgical procedures required for
diagnosis or therapy of uveitis, and surgery for macular holes and
subretinal neovascularization. Jaffe's primary research is aimed at
understanding the factors that trigger and perpetuate inflammation and
intraocular wound healing in diseases such as uveitis and proliferative
vitreoretinopathy and to develop novel drug delivery methods to treat a
variety of ocular diseases. He was recently honored among the Best
Doctors in America.
Phone
919.684.4458
Fax
919.681.6474
Research Interests
-
Methods to deliver drugs to treat or prevent ocular inflammation,
macular edema, retinal degeneration, and proliferate eye disease.
-
Cell biology of retinal pigment epithelial cells in ocular proliferate
disease and ocular inflammation.
-
Methods to prevent cell proliferation in retinal diseases including
proliferative diabetic retinopathy, macular degeneration and
proliferative vitreoretinopathy.
-
Vitreoretinal surgery innovations.
Representative Publications
-
Jaffe GJ, Ben-Nun J, Guo H, Dunn JP, Ashton P. Fluocinolone Acetonide
Sustained Drug Delivery Device to Treat Severe Uveitis. Ophthalmology
107:2024-33, 2000.
-
Wang X-C, Jobin C, Allen JB, Roberts WL, Jaffe GJ. Suppression of
NF-kB-Dependent Proinflammatory Gene Expression in Human RPE Cells by
a Proteasome Inhibitor. Invest Ophthalmol Vis Sci 40:477-486, 1999.
-
Jaffe GJ, Yang CS, Wang X-C, Cousins SW, Gallemore RP, Ashton P.
Intravitreal Sustained-Release Cyclosporine in the Treatment of
Experimental Uveitis. Ophthalmology 105:46-56, 1998.
-
Merrill PT, Kim J, Cox TA, Betor CC, McCallum RM, Jaffe GJ. Uveitis in
the Southeastern United States. Curr Eye Res 16:865-874, 1997.
-
Jaffe GJ, Brownlow R, Hines J. Modified External Needle Drainage
Procedure for Rhegmatogenous Retinal Detachment. Retina 2002, in press.
|
