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Assistant Professor of Ophthalmology
Glaucoma Service
Residency Program Director
Medical school
University of Florida, College of Medicine
Internship
Emory University Hospital
Residency
University of Florida
Fellowship(s)
Duke Eye Center
Background
Pratap Challa, MD, specializes in glaucoma management including medical,
laser, and surgical treatments for glaucoma. He is experienced in all
forms of glaucoma surgery, including trabeculectomy with antimetabolite
therapy, tube implants, cataracts, and revision of glaucoma surgery.
Challa is also the director of the Duke University residency program and
oversees resident training and education.
As a physician-scientist investigator, Challa has a special research
interest in the genetic basis of inherited eye diseases. He investigates
the genetic basis and cause for pseudoexfoliation syndrome and
pseudoexfoliation-associated glaucoma. He actively recruits patients to
participate in these studies and investigates the molecular basis for
these disorders. He also has a novel drug delivery program involved in
developing long-term delivery devices for glaucoma medications. He also
investigates novel compounds that may eventually be used for treating
glaucoma.
Phone
919.684.3283
Fax
919.681.8267
Research Interests
Challa's primary research interests are directed at both basic science
and clinical research in the subspecialty of glaucoma. His basic science
interests are on the genetic basis of inherited eye disorders. He is
focused on examining transcriptional profiles in disorders such as
Pseudoexfoliation Syndrome (PEX). PEX is one of the leading causes of
glaucoma worldwide. This research is aimed at identifying candidate
genes for several types of glaucoma. He also has research interests in
the development of novel drug delivery devices and new drug therapies,
such as peptide-based therapies for glaucoma. In addition to basic
science research, he also has clinical research interests including
evaluating the effectiveness of new glaucoma therapies.
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